Consensus based Risk Staging System (CRSS) calculator for Multiple Myeloma (version 1.0)
Joint collaborative work of Laboratory Oncology Unit, Dr. B.R.A. IRCH,
AIIMS, New Delhi and SBILab, Department of ECE, IIIT-Delhi, New Delhi
Principal Investigators: Prof. Ritu Gupta, AIIMS and Prof. Anubha Gupta, IIITD
Description: CRSS is an efficient and robust AI-enabled
risk-staging system for MM patients that utilizes ethnicity-specific
cutoffs of key prognostic parameters.
It predicts the risk stage of a patient depending on the values of the
seven parameters- age, albumin, β2m, hemoglobin, calcium, eGFR and high
risk cytogenetic abnormalities [del 17p; t(4;14); t(14;16)].
It's utility has been validated for Newly diagnosed Multiple Myeloma (NDMM) patients.
Risk-stratification achieved by AI assisted CRSS is able to better
separate the patients into different risk groups as compared to RISS
It is a reliable and efficient tool for upfront risk stratification of
MM patients and can help the clinicians/doctors in designing and
providing effective therapy to MM patients.
Please cite us if you use CRSS calculator in your research work.
Farswan A, Gupta A, Sriram K, Sharma A, Kumar L, Gupta R.
Does ethnicity matter in multiple myeloma risk prediction in the era of
genomics and novel agents? Evidence from real-world data. Front Oncol
If information on ethnicity and genetic abnormalties is not available, then you can use MRS
calculator designed by us. MRS is also an advanced AI-supported
calculator that works efficiently in the absence of cytogenetic
abnormalities, that is, it predicts the MM cancer risk stage using the
six parameters of the patients- age, albumin, hemoglobin, β2M, calcium